Erispal is an anti-inflammatory drug. The active substance of the drug is Fenspirid. Produced in the form of tablets and syrup from cough. It has antihistamine and antispasmodic effect.
Release form and composition
Erispal is available in the following forms:
- Pills. White color, round shape. Do not have a specific smell and taste. Produced in packaging for 30 pieces. Active ingredient: hydrochloride phenspirid. Auxiliary substances: Hypromellos, silicon dioxide, povedium, magnesium stearate, titanium dioxide, glycerol, calcium hydrophosphate, macrogol 6000.
- Syrup. Transparent yellow liquid. It is possible to form a precipitate. Available in bottles of 150 ml. Active ingredient: hydrochloride phenspirid. Auxiliary substances: licorice extract, flavoring supplement, sunstenet yellow, sucrose, glycerol, spharic, water, potassium sorbate, propyl aprichedroxybenzoate, methylpaultydroxybenzoate.
Erispal is an anti-inflammatory drug. Thanks to the components, the components have spasmolitical, anti-inflammatory and antihistamine effect.
Fenspirid prevents the emergence of bronchokonstriction, reduces the process of exudation. The effect of the drug is based on the slowdown in the production of biologically active substances. These include histamine, bradykin, serotonin. Erispal blocks alpha-adrenoreceptors.
The drug is well absorbed from the gastrointestinal tract. The maximum concentration of Erispal in the blood is reached 2.5 hours after its reception. The half-life is 12 hours. Most of the drug is excreted by the kidneys, the remaining intestinal.
Indications for the use of Erespal
Erispal is used in the presence of inflammatory diseases of the upper and lower respiratory tract. The main indications for the purpose of the drug include:
- Complex therapy of bronchial asthma;
Due to the variety of output forms, the drug is used in pediatric practice. Dosage, multiplicity of reception, as well as the duration of the course of treatment are determined individually. There are general therapeutic recommendations for receiving Erexpal. These include:
- Tablets are accepted before meals. The daily dose is 80 mg 2-3 times a day depending on the severity of the state. The average duration of the course is 14 days.
- Syrup is appointed both adults and children from 12 years old. The daily dose is 45-90 ml. This corresponds to 3-6 dimensional spoons.
Restrictions for assigning Erispal are the following states:
- Individual intolerance to the components of the drug;
- Age under 2 years old.
Erispal syrup is not appointed by persons suffering from diabetes mellitus, fructose intolerance, glucose-galactose malabsorption.
During the reception, the following side effects may arise:
- decrease in blood pressure;
- pain syndrome in the epigastric region;
- Stool instability;
- sharp decay of forces;
- swelling quinque;
- Skin itch.
These symptoms require the abolition of the drug and appeal to the doctor.
If the therapeutic dosage of Erespal is exceeded, the risk of developing symptoms of overdose increases. These include:
- emotional lability;
If the above symptoms appear, it is necessary to stop taking the drug and consult a doctor. In severe cases of overdose, hospitalization is required. Specific antidote does not exist. Symptomatic therapy is shown.
Currently there are no studies on the interaction of Erexpal with other drugs. It is known that his joint appointment with sedative drugs leads to strengthening the impact effect.
In the presence of certain testimony, Erispal can be assigned together with expectorant drugs. For example, Lazolvan, ATSC, Ambroben, Ambroxol.
Analogs of Erespala
In situations where the reception of erections is impossible for any reason, it is recommended to use it analogues. These include:
What is better: Erispal or Erispirus?
Erispirus is an anti-inflammatory drug that has an antibronchoconstrictor action. The active substance of the drug is Fenspirid. Produced in the form of tablets and syrup for intake. Erispirus has anti-inflammatory, antihistamine and armored effect. Indications for the preparation of the drug are:
- Complex therapy of bronchial asthma.
Erispirus is not recommended to be used during pregnancy and lactation, in childhood and in the presence of individual intolerance to the components of the drug.
Erispal and Erispirus are considered complete analogues of each other. Preparations contain the same active substance, mechanism of action, formation and dosage form. Drugs are used in the presence of inflammatory diseases of the upper and lower respiratory tract. Differences between drugs are concluded in manufacturers and auxiliary substances. Erispal is produced by the Pharmaceutical company "Servier", Erispirus - Sandoz. In the composition of the erections of the additional substance is the Loccant. It gives an expectorant effect, stimulating the detection of sputum.
What is better: Erispal or Ascoril?
Ascoril is an expectorant combined drug. The active substances of the drug are Bromgexin, Gweefenesin, Menthol and Salbutamol. Produced in the form of tablets and syrup for intake. Ascoril has a musolitic, bronchor and expectorant effect. The main indications for the purpose of the drug include:
- Complex therapy of bronchial asthma;
- pulmonary tuberculosis;
- whooping cough;
- Emphysema of the lungs.
The drug is not used during pregnancy and lactation, with individual intolerance of its components, glaucoma, ulcerative disease of the stomach or duodenum, diabetes mellitus of any type, renal and hepatic insufficiency of the heavy stage.
Erispal and Ascoril belong to one pharmacological group. Preparations are used to relieve cough. Drugs have similar form forms, prescribed in pediatric practice. Differences between medicines are as follows:
- Ascoril exhibits greater efficacy with dry cough. Erispal is prescribed with any type of cough;
- Preparations have different active ingredients. The active component of Ereshpal is Fenspirid. The active substances of Ascoril are considered bromgexine, gvifenesin, menthol and salbutamol;
- Ascoril has a wide range of contraindications for destination. The restriction for the use of ereser is the individual intolerance to the components of the drug.
Before purchasing medicines, it is recommended to consult a doctor. Self-medication can lead to negative consequences.
What is better: Erispal or Fluditec?
Fluditec - Mukolithic drug. It has an expectorant action. The active component of the drug is carbocysteine. Produced in the form of a syrup for intake. Indications for the destination of the fluidka are:
- bronchial asthma;
- Preparatory period before the behavior of bronchoscopy.
Doctors do not recommend using fluudichetics in the presence of individual intolerance to the components of the drug, ulcerative disease of the stomach or duodenum, exacerbation of chronic glomerulonephritis, cystitis, as well as in 1 trimester of pregnancy.
Erispal and fluudico are fluculatic drugs that have an expectorant effect. Medicines are prescribed in the presence of cough symptoms. The active substance of Erepal is Fenspirid. As part of the fluid, the current component is considered carbocysteine. Erispal is produced in the form of tablets and syrup. Fluditec is performed only in the form of a syrup for receiving inside. Dosage preparations are selected individually attending physician.
What is better: Erispal or Bromgexin?
Bromgexine is a drug relating to the group of stimulants of the motor function of the respiratory tract. The active substance of the drug is bromgexine. The drug has a musolitic, antitussive and expectorant effect. Available in the form of tablets, drops and medicines. Bromgexine is prescribed in the presence of the following diseases:
- bronchial asthma;
- Emphysema of the lungs.
The drug should not be appointed with the individual intolerance of its components, ulcerative ulcer of the stomach or duodenum, as well as during pregnancy and lactation.
Erispal and Bromgexin are prescribed in the presence of inflammatory diseases of the upper and lower respiratory tract. Preparations have many differences:
- The active substance of Erepal is Fenspirid. The current component of Bromgexin is considered bromgexine;
- Fenspirid contributes to the dilution of mucus and rudely affects coughing receptors. The action of bromgexin is to stimulate the activity of the cilia of the bronchial walls. As a result, there is a soft removal of sputum;
- The form of the erection of the ereser is tablets and syrup for intake. Bromgexine is produced in the form of droplets, tablets and medicines.
What is better: Erispal or Siresp?
Siresove is an anti-inflammatory drug that has an antibronchoconstrictor action. The active substance of the drug is Fenspirid. Released in the form of syrup. Siresp has an armored, anti-inflammatory and antihistamine effect. Indications for the purpose of the drug are:
- bronchial asthma;
Contraindications for the use of sebs are pregnancy and lactation period, age under 2 years old, individual intolerance to the components of the drug.
Erispal and Sirespass belong to one pharmacological group. Drugs have similar composition, mechanism of action, testimony for destination and side effects. The difference between drugs is in the form of release. Erispal is made in the form of tablets and syrup. Siresp is produced in the form of a syrup. The decision on which of the medicines will be the most effective in the diagnosed disease, takes the attending physician.
What is better: Erispal or Lazolvan?
Lazolyvan refers to the number of expectorant musolitic medicines. The active substance of the drug is ambroxol. Released in the form of syrup, pupin, solution for inhalation and intake, as well as tablets. Lazolyvan has a secretlytic and secretomotor effect. The main indications for the purpose of the drug include:
- bronchial asthma;
- chronic obstructive pulmonary disease;
- Bronchiectatic disease.
Lazolyvan is not used in 1 trimester of pregnancy, during breastfeeding and with individual intolerance to the components of the drug.
Erispal and Lazolyvan are prescribed to facilitate cough. The active substance of Erepal is Fenspirid. Ambroxol is considered as a valid component in the lazole component. Erispal exhibits greater activity in the treatment of dry cough. The Lazolyvan is prescribed for wetting the sputum and facilitating its removal from the body. Erispal is made in the form of tablets and syrup. Forms of the release of the Lazolyvan are syrup, pupquils, tablets, a solution for inhalation and intakes. In the presence of certain indications, these drugs can be assigned together.
What is better: Erispal or Rengalin?
Rengalin is an antitussive drug of a comprehensive action. The active substances of the drug are antibodies to bradykinin, histamine and morphine. Produced in the form of tablets and a solution for receiving inside. Rengalin has an anesthetic, anti-inflammatory, antispasmodic, anti-allergic and anti-edema effect. The effect of the drug is based on the oppression of the excitability of the cough cerebral center. Similarly, the medicine prevents a cough reflex. The testimony for destination Rengalin includes:
Restrictions for the preparation of the drug are the individual intolerance to the components of the drug, the period of pregnancy and lactation. Diabetes mellitus - contraindication for the use of syrup.
Rengalin and Erispal are appointed to facilitate cough arising against the background of inflammatory diseases of the upper and lower respiratory tract. Differences between drugs are as follows:
- The active substance of Erepal is Fenspirid. As part of the Rengalina, the active components are considered antibodies to bradykinin, histamine and morphine;
- Erispal is made in the form of tablets and syrup. Rengaline release forms are tablets and a solution for intake;
- Erispal is produced by a European pharmaceutical company. Rengalin is a drug of domestic production.
In some cases, drugs can be used as part of comprehensive therapy.
What is better: Erispal or Ambroxol?
Ambroxol is a musolitic preparation with an expectorant effect. The active component of the drug is ambroxol hydrochloride. Produced in the form of tablets, syrup, solution for inhalation and intakes. The main indications for the assignment of ambroxol include:
- Complex therapy of bronchial asthma;
- lung abscesses;
The drug is not recommended to be prescribed in the presence of ulcerative disease of the stomach or duodenum, individual intolerance to the components of the drug, as well as in 1 trimester of pregnancy.
Erispal and ambroxol are prescribed with cough. The active substance of Erepal is Fenspirid. As part of the ambroxol, the active ingredient is ambroxol. Due to the various set of components, drugs are characterized by mechanisms of action. Erispal is produced in the form of tablets and syrup. Ambroxol is made in the form of tablets, syrup, a solution for inhalation and intake. Before purchasing drugs, it is recommended to consult with your doctor. The specialist will appreciate the general condition, selects the correct dosage, the multiplicity of reception and the duration of the course of treatment.
What is better: Erispal or Fenspirid?
Fenspirid is an armored anti-inflammatory agent. Its active substance is Fenspirid. The drug has anti-inflammatory, antihistamine and anti-asthma effect. Produced in the form of tablets and syrup for intake. Indications for the purpose of the drug are:
- Complex therapy of bronchial asthma.
The drug is not used in the presence of individual intolerance to its components, under the age of 14, during pregnancy and lactation.
Fenspirid and Erispal belong to one pharmacological group. Preparations have similar composition, mechanism of action, formation form, indications and contraindications to use. This allows you to consider them with complete analogues of each other. Erispal is produced by a European pharmaceutical company. Fenspirid is a drug of domestic production. Before purchasing medicines, it is recommended to consult a doctor. The specialist will be able to assess the severity of the state and select the necessary dosage of the drug. Self-meditation leads to negative consequences.
What is better: Erispal or Eldon?
Eldon is an anti-inflammatory drug with an antibronchoconstrictor action. The active substance of the drug is Fenspirid. Produced in the form of tablets and syrup. It has an armored, antihistamine and anti-inflammatory effect. The main indications for destination of Eladone include:
- Complex therapy of bronchial asthma;
Contraindications for the appointment of the drug are increased sensitivity to the components of the drug, pregnancy, lactation, age under 18 years of age.
Erispal and Eldon can be considered absolute counterparts. Preparations relate to one pharmacological group, in their composition there is the same active ingredient. This ensures similar mechanism of action, indications and contraindications for destination. Both drugs are produced in the form of tablets and syrup. The difference between Eladone and Erispal lies in manufacturers. Eldon is produced by a domestic pharmaceutical company. Erispal - European drug.
What is better: Erispal or Ambroben?
Ambroan is an expectorant musolitic drug. The active substance of the drug is ambroxol. Available in pills, capsules, syrup, solution for inhalation and intake, as well as a solution for intravenous administration. Ambroben contributes to the wet wet and relief of its disheavage. Indications for the preparation of the drug are:
- Complex therapy of bronchial asthma.
Ambroben is not appointed in 1 trimester of pregnancy, during lactation, in the presence of individual intolerance to the components of the drug, under the age of 6 years.
Erispal and Ambroben are prescribed to facilitate cough. The active substance of Erepal is Fenspirid. Ambroxol is considered to be Ambroxol as part of the acting component. Erispal is produced in the form of tablets and syrup from cough. Ambrone has more diverse forms of release. The drug is produced in the form of tablets, capsules, syrup, solution for inhalation and intake, solution for intravenous administration. In some cases, the sharing of medicines is not excluded. However, the appointment performs the attending physician after a preliminary inspection and appropriate diagnosis.
Erispal in the form of a syrup is used in pediatric practice for children over 2 years old. The prescription of the drug at an earlier age is contraindicated.
Joint admission of alcoholic beverages and erections is prohibited. This is due to the fact that alcohol enhances the sedative effect of the drug. As a result, side effects may appear. These include weakness, headache, sharp decay, increased drowsiness.
During pregnancy and lactation
Currently, there are no objective data on the influence of the erector on the fetus during pregnancy. In addition, there is no information about the ability of the drug to penetrate breast milk. In this regard, doctors do not recommend using a medicine during pregnancy and lactation.
Terms of sale
Erispal refers to the number of prescription drugs. Before his acquisition in the pharmacy must be consulted with a doctor. The specialist will evaluate the state, will determine the correct dosage, the multiplicity of reception and the duration of the course of treatment.
Erispal should be kept in a place protected from light and children at a temperature not higher than +25 degrees.
The shelf life of Erispal depends on the form of its release. Syrup can be used for 3 years from the moment of the drug. The shelf life of the tablet forms of Erespal is 2 years. It is not recommended to use the drug after the expiration of the specified time.
"Laboratories servier Industry", France.
List of references:
- State register of medicines;
- Anatomy-therapeutic-chemical classification (ATX);
- Nonological classification (ICD-10);
- Official instruction from the manufacturer.
What to buy from cough? Have you ever had such a question to contact the pharmacy workers? Do you know that such questions put them in a dead end?
The fact is that the range of preparations aimed at combating cough is very diverse. In the arsenal of pharmacists there are funds in different dosage forms, differing in the principle of action. Cough cough - Return, because this symptom accompanies many diseases having a different origin. Therefore, before ordering the medicine, it is important to find out how to treat the cough specifically in your case.
Figure 1 - How to treat cough?
What is cough?
A familiar symptom is a protective reaction of the body to various stimuli - coughing, we clean the respiratory tract. Cough can be a symptom of the disease (inflammatory, allergic) or irritation reaction:
- mechanical (dust);
- chemical (cigarette smoke);
- thermal (cold or hot air).
The clearing mechanism is quite complicated. Such a reaction of the body occurs in response to irritation of nervous endings, and it may be associated not only with diseases of the respiratory tract, but also with other problems.
Figure 2 - Respiratory System
Diseases of hearing aisters, violations in the work of the cardiovascular system and brain, the pathology of the esophagus, the stomach - cough may also appear in these and other cases. Therefore, in order to answer the question of how to choose a child's cough or in an adult, a doctor needs to establish a source of problem.
What else needs to know to understand which cough pills help better?
Before writing a patient with Lazolvan or the ACC, the doctor studies the features of cough. And it can be dry, barking, supervised, silent, etc. - And all this speaks about different diseases. In one case, there is a vocabulary injury (silent or sapper cough), in another - about obstructive bronchitis (deaf cough), in the third - about inflammation ("barking" cough).
Briefly list the most pronounced characteristics that can distinguish an ordinary person who has no special education:
- The cough is dry and wet (dry can go to wet).
The dry cough is not accompanied by expectoration and the release of the mocroid.
This symptom is manifested in inflammatory diseases of the bronchi, larynx and trachea, during pleurisy, as well as at the initial stages of sharp viral infections and in allergies.
People suffering from heart disease (including heart disease), as well as patients who have been diagnosed with nerve diseases (psychogenic cough arising after stress, etc.) on dry cough.
Drugs are prescribed depending on the characteristics of the disease (usually these are anti-sewing remedies).
With such a cough, there is a discharge of sputum (secret, mucus). It may differ in color (it helps to establish the correct diagnosis).
With a wet cough, anti-flame remedies are not used. Patients recommended expectorant, mercolytic, antihistamines and combined drugs.
Wet cough is characteristic of respiratory diseases.
- The duration differences the cough sharp and chronic. Sometimes the patient has single periodic attacks, sometimes they are permanent (permanent cough requires immediate treatment, as it represents a real threat to life).
It usually happens in patients with sharp viral and respiratory diseases.
Duration - within 3 months (subject to treatment).
Chronic cough bothers the patient constantly.
It lasts more than 3 months and is usually a symptom of chronic respiratory diseases or a sign of cardiac, nervous and oncological diseases.
What helps from the damp and dry cough?
So, when choosing a medication, it is important to accurately determine the dry cough or wet. The correct appointment will be able to make a doctor: the therapist will help, and the child should be shifted to the pediatrician. In difficult cases, it may be necessary to assist the pulmonologist, an infectiousnessist, an allergist.
Figure 3 - Fast Help for Cough
With a wet, or the cough productive, mercolytic and expectorant means are effective.
Mulitatic drugs. Mulcolics contribute to the wet wet (secretion), due to which it is easier to display. Drugs of this group are prescribed in the treatment of bronchitis, pneumonia, tracheitis and a number of other respiratory diseases. There are liquefying and indirect mercolics.
Multic means of direct action act directly to bronchial glands. Moorgulators (reflexive-action flourities) cause irritation of the nervous endings of the stomach mucosa.
This group of drugs include acetylcysteine, ambroxol, the ACC, Bromgexin, Carbocysteine, Koldrex, Lazolyvan, Mukaltin, Soberod, etc. Mukolitics can also be used in patients with dry cough, but as part of combined therapy (along with other auxiliary drugs) and under control Doctor.
Expectaurant. Receiving these drugs is shown in cases where it is necessary to activate the process of cleansing the respiratory tract. When taking medication, irritation of the mucous membranes of the bronchi occurs, and as a result, cough arises, which allows to withdraw a sputum (remember: Mukolithics dilute the sputum, expectorant contribute to its better removal). The list of the most famous expectorant means includes Givephenesin, Stoptussin, Camprex Broncho. The main ingredients of many expectorant means are plant extracts, for example, the formula of many well-known altecia includes the roots of Altea.
Anti-inflammatory funds with bronchhalytic and / or expectorant effect can be recommended for the treatment of wet cough in comprehensive therapy. This category includes Ascoril, Prospan, Sinuperet, Gedelix, etc. Feature of this group of drugs: They help remove spasm in the respiratory tract, which may also cause cough.
In the treatment of dry cough, preparations that depress cough receptors are usually used - means that affect the centers of the brain, nerve endings or mucous membranes. The main task of central drugs is to suppress (block) a cough reflex that isolates the patient. Usually prescribed with chronic forms of respiratory diseases, as well as with cough. The patient may write funds containing opioids (codelk), or drugs without a narcotic effect (synecode, glazatent, libeksin). The above funds are not prescribed with a wet cough, because instead of helping, they drive deep off the disease. With dry cough form, funds can be used that contribute to the discharge and removal of sputum (Lazolvan, Ambrohexal, Stoptussin, etc.).
Figure 4 - Ask your attending physician, which is better from dry cough
Many antitussive tools immediately have several positive effects. So, the syrup of the plantain Herbion has anti-inflammatory, expectorant, anti-inflammatory and antimicrobial effects. Synecode helps to remove spasms in bronchi and reduce inflammation, Liebeksin expands bronchi and anesthesia, etc.
In a separate group, comprehensive action preparations were made - they are prescribed a strictly physician (usually used for obstructive syndrome therapy). These medicines have an expectorant, bronchor, anti-inflammatory effect, and help reduce cough reflex. These include Stoptussin and Broncholitin, Tussin Plus and Lorein, Protiazine, Hexapnemum, Butamirat, etc.
Most cough drugs are implemented in a pharmacy without a recipe (with the exception of some drugs of central action that have a drug effect). It is no secret that the diseases of the respiratory tract we are often treating independently without addressing professional help. Therefore, the situation often occurs when the sick person is trying to figure out:
- How to choose a remedy for a wet cough for children?
- What is better - ambroxol or ATSC?
- Is it possible to take Perptissine and Mukaltin together?
- What is better from cough - syrup or pills? etc.
Figure 5 - Is it possible to use an ambroxol with a dry or wet cough?
The problem is that a single drug that will be equally efficient and safe for all patients without exception does not exist. The only opportunity to determine the best expectorant or flourity of cough for a particular person is to survey the doctor. The specialist appoints pharmaceutical preparations, focusing on:
- The diagnosis (symptoms and complaints are studied, surveys are carried out - analyzes, x-rays). If it is a dry cough, the therapy scheme is one, if the wet is another, if the nervous is the third.
- Patient age and general health. Each medication has restrictions on age and recommendations on the use of one or another drug form of the drug. For children, the optimal option may be syrup or pastili. Patients with a diagnosis of "Gastritis" will have to abandon the effervescent forms of pharmaceuticals, etc.
For example, answering the question that it is better than the ACC or Ambroben for a child, the doctor will definitely clarify the age (the infants are suitable for the baby or ambroben syrup, while the ACC is prescribed to children from two years).
- The presence of contraindications. Drugs that can be taken without exception, there is practically no. Many restrictions - for pregnant women and children, as well as people with allergies to certain components, as well as severe internal organs.
- The presence of complications. Medicines from the same group may have the same effect, but different composition and principle of operation. This is an important point that is taken into account in the treatment of different states. For example, if the therapy requires additional use of antibacterial agents, then choosing between the Lazolyvan and Ambroxol, the doctors often prefer the latter, since this drug allows you to reduce the dose of the antibiotic.
For a more visual example, you can compare the appointment of such well-known drugs, like Lazolyvan and Ascoril (many patients are interested in that it is better and possible to take them at the same time).
Above, we already found out that Ascoril is an anti-inflammatory drug with an expectorant effect, and Lazolyvan is an indirect action flour. Both means are used in the treatment of a wet cough resulting from various pathologies of the respiratory tract.
The list of readings for both drugs is similar (ascoril it is wider, since it is a combined formula). However, due to the fact that the compositions of drugs differ significantly, the list of contraindications and side effects they have different. For example, Ascoril is not prescribed with hypertension, eye pathologies and stomach ulcers, as well as with diabetes and hormonal disorders, whereas the Lazolyvan has no such contraindications. If Ascoril can be taken to children only from 6 years, then injections and syrup Lazolvan can recommend the smallest patients.
Another important point is the form of drug release. Lazolyvan is presented in a wider range: in addition to syrup and tablets, as in the case of ascoril, you can buy a lazolvan in capsules, in the form of a solution for injection and spray.
The simultaneous use of both means is allowed, but only under the control of the doctor, since the risks of the development of adverse reactions increase. It should also be mentioned that during combined therapy, the lazolvan is preferable, since it is allowed to combine with many pharmaceutical agents (including with corticosteroids, diuretics, etc.).
We conclude: Before you prefer some tool, you need to consider many factors. Therefore, the most correct decision is not to risk, engaged in self-medication, and clarify what to buy from cough, at your attending physician, having coordinated with a specialist the possibility of use and combination of different drugs.
Video 1 - What is cough and how to deal with him?
Not being an antibiotic, Fenspirid is still important in the treatment of respiratory diseases, especially when they are inclined to obstruction. This substance is part of the drugs Erispal and Erispirus. The differences between these drugs, the mechanism of their action and some other characteristics are described below.
There are contraindications, consult with a specialist
Both drugs are in the pharmaceutical group of vasodilators and anti-inflammatory funds. The active substance in their composition - Fenspirid . Release form: Tablets of 80 mg and 2 mg / ml syrup. Therefore, we can conclude that by the main characteristics of Erispal and Erispirus - this is the same.
Erispirus and Erispal - What is the difference?
Updated On February 14, 2019, Roszdravnadzzor decided to withdraw the "Erespal" and analogues (including Eyrepyrus) from the sale due to the risk of heart rate disorders.
A small difference between drugs is the one who produces them. Erispal is a product French Les Laboratoires Servier, which, among other things, is produced at the Russian Pharmstandart-Lexere Enterprise. Erispirus releases Sandoz ( Slovenia ). Depending on this, the composition of forming substances is slightly different (look in more detail on the package).
By the way, this is the difference in Erispal from Erispirus: he Contains solidity extract among the auxiliary components which in folk medicine is used as a flour.
From consumer reviews it follows that the therapeutic effect of the medication is very similar. Many patients note improvement (decrease in cough and shortness of breath) after a short time. However, it is sometimes reported on side effects in the form of tachycardia, nausea or allergic reactions.
It should be borne in mind that the drugs under consideration Contain histamine receptor blocker Therefore, they cannot be used, guided only by approval on Internet sites. Do not forget to get a medical advice on the correct treatment of your disease. Overdose may be dangerous, therefore the duration of the reception and daily amount of medication must be appointed by a doctor.
How does Fenspirid act?
Our body has many ways to protect against infection, one of which is the so-called "arachidonic acid cascade". The products of the metabolism of this unsaturated fatty acid contained in the membranes of many cells cause the formulation of inflammation mediators. These include prostaglandins, thromboxanes, leukotrienes. According to the action, they are similar to histamine: cause increased permeability of vessels (swelling) and attract inflammation of the cell of the immune system to the site.
Arachidonic acid "comes out" from membranes and launches this inflammatory cascade under the action of phospholipase-A2 enzyme. Erispirus, an analogue of the ereser, as well as he, have a strong anti-inflammatory effect, because the phenspiride contained in them oppresses the activity of phospholipase.
In addition, blocking Histamine H1 receptors H1, Fenspirid inhibits the inlet of calcium ions to the cell and the release of arachidonic acid. Since this is one of the first reactions in the launch of inflammation, the "Arachidonic acid cascade" is interrupted as a result:
- Migration of neutrophils in place of inflammation decreases,
- The concentration of active forms of oxygen and free radicals in it is reduced.
- Relaxing smooth muscles of bronchi,
- The aggregation of platelets is reduced, which helps to improve the microcirculation of the mucous membranes of the respiratory tract,
- Swells of mucous membranes decreases.
Efficiency of analog
In international evidence-based medicine, there was no special comparison of the results of the treatment of Fenspirid and placebo, since it is not registered for use in the United States and many European countries. However, in domestic studies there are many evidence of its therapeutic efficacy and relatively small toxicity.
For example, in patients with chronic inflammation of the subordinate sinuses of the nose of Fenspirid in a month, the indicators were 3 times compared with the placebo group. After 2 months, the mucinous purulent discharge from the nose cavity was 5 times less than in the group without treatment.
Reducing the shortness of breath, decrease in the wet separation and cough resistance was observed in patients with obstructive lung diseases, which took Fenspirid for 2 Table / Day for 1.5 months. Since the medicine is well tolerated, the course can be extended to six months, and the side effects are insignificant (about 5%).
A large-scale study of Fenspirid in the practice of treating children with respiratory diseases was carried out. More than 1,000 doctors of the domestic clinics and more than 5 thousand children participated in it. It turned out that when taking the syrup of Ereshprekala for 7 days, ORZ symptoms disappear for 2-3 days earlier than in a group that did not accept the drug. Only 2% of patients had side effects in the form of nausea, diarrhea or urticaria.
How to take and price the course
Let's calculate how much syrup is needed for the treatment of cough with ARZ. According to the instructions, 2-4 spoons or 30-60 ml are needed for a child older than two years. In a bottle of 150 ml, it means that it is enough for 5 days at minimum flow, and at the maximum - by 2.5. If the doctor prescribed the drug for 5-7 days, not less than 2 bottles. The cost of one package is ranging from 350 to 450 rubles, and the course of treatment will cost 700-900 rubles. Erispirus syrup costs approximately 2 times cheaper.
Erispal tablets prescribe adults for 3 pcs / day, so it will take 1 package for 10 days (30 Table), the cost of which is about 400 rubles. The price of analogue is approximately 2 times lower.
Popular in Russia, the anti-kilumed agent "Erispal" was outlawed. Both forms of the drug - syrup and tablets - removed from sale and are now removed from pharmacies with return supplier. We tell me what is happening and is it possible to choose a replacement with a medicine that many in our country consider almost the most effective and unparalleled?Yaromir Romanov / Znak.com
From the end of last week in Russian pharmacies, both forms of "Erespala" - a medicinal product, which is known since the end of the 70s and has become great popularity in Russia as a drug used for wetting and withdrawing sputum with a strong dry cough. Pharmacies follow the prescription of the Federal Service for Supervision of Health of the Russian Federation (Roszdravnadzor), which on February 14 reported the withdrawal of "Erespala" in syrup and tablets from the treatment throughout Russia.
Roszdravnadzor himself thus responded to the message of the French company "Laboratory Servier" - the manufacturer of "Erespala". Back in late January, the Russian representative office of the pharmaceutical giant notified the Ministry of Health of the Russian Federation and Roszdravnadzor on the results of the next preclinical studies, which gave reason to doubt the safety of the popular drug. Moreover, on February 11, the "Laboratory of Servier" themselves announced the revocation of "Erespala" from the appeal in Russia. As stated on the company's website, such a decision was made "in connection with the emergence of new data that suggests that this drug may cause heart rate disorders."
"Erispal" is really dangerous?
Today it is definitely impossible to argue. Review and withdrawal, which, by the way, occur today in other countries, in the statement of Roszdravnadzor are called "a routine tool for the prevention of threats to the health of patients during the period of additional study of the new drug safety data". Speaking easier, the medicine was not forbidden, but "put on the stop" - until the data were received, excluding suspicions about the side effects of the drug.It is important that the initiative comes from the manufacturer itself, which thus decided to be reinsured - from concerns that in the future it would have to deal with numerous and very impressive claims from consumers. On the sites of Pharmacies "Erispal" is no longer for sale. But you can buy its full counterparts - other preparations based on Fenspirid Znak.com
In the manufacturer's information letters, as well as organs regulating the drug market in Russia, the basis for the review of the drug is called the potential risk of adverse effect on the rhythm of the heart. This reaction showed research conducted on animals. At the same time, according to the data that leads Roszdravnadzor, over the past 10 years, in patients who used Erispal in Russia, not a single severe reaction to the active substance of the drug - Fenspirid was not revealed. This is an international non-proprietary name, which is used, for example, doctors when prescriptions are discharged.
"All the time since 1973, there are only five post-registration ( That is, the period relating to the period after issuing a medication to the manufacturer of a registration certificate for it - approx. Znak.com ) Cases of development of the elongation of the Qt interval on the electrocardiogram and pyruetete tachycardia, and they all had a favorable outcome. In addition, from the moment of receipt of the first registration certificate in the world, not a single case of such adverse reactions was detected in children, "the statement said, which was distributed on February 15, signed by Yana Rostovtsevaya, managing director of Servier in Russia.
By the way, the fact that "Erispal" was generally sold (in any case, they had to sell) on the recipe, is also an extremely important item. She suggests that the drug may have contraindications and they have been well known before. Their descriptions are easy to find on the Internet. And if you believe this data, the drug, for example, is not recommended to give pregnant and nursing mothers, as well as children under the age of two years. Most often, the "Erispal" reacts the digestive system, and the cardiovascular can answer moderate tachycardia, that is, a painful rapid heartbeat.
How can I replace "Erispal"?
Experts say that now we are dealing with a typical consumer stir. Many patients and even the doctors are really convinced that "Erispal" is the best representative of his medicinal group. And ready to prove with a support for personal experience. Anyway, it is not necessary to forget that this is just one of the several drugs based on Fenspirid.They removed from sale only it, and the rest can be used without difficulty - to make sure it is enough to look at any pharmacy site.
Roszdravnadzor, however, requested the latest data on the efficiency and safety of manufactured drugs from manufacturers of other registered medicines. And, as they say on the site of the supervisory department, after studying the entire array of domestic and foreign data on the safety of Fenspirid in the near future, proposals for further turnover of these drugs will be sent to the Ministry of Health of Russia. It is possible that manufacturers of analogues, following the example of "Servier's laboratories", will begin to call their products from the market.
While this did not happen, you can use a fairly wide range of medicines, including Eldon, Erispirus, "Epistat", "Siresp", "Cleather", "Folden" and others. Middle price variation - from 80 to 370 rubles (" Erispal ", by the way, was not the cheapest alternative, but it was laid in this price range). All these drugs are also available in different forms and can be proposed by provisions if you show them a recipe with the mention of Fenspirid. If doubts arise, advise with the attending doctors.
If the Fenspirid itself will be outside the law, nothing terrible will occur, experts say. Also assimilated drugs based on ambroxol, bromhexine, acetylcysteine also help unpleasant manifestations. "They lived, in the end, somehow to Fenspirid," the expert in the field of pharmacology shrugged in a conversation with Znak.com. However, the other option is not to be excluded and another option, favorable for Eraspal, with its full rehabilitation and return on the shelves of pharmacies.
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With the arrival of cold weather, the season of various colds and infectious diseases opens. Consistent temperature differences and high humidity contribute to the reduction of immunity ability to deal with undesirable infections in patients of all ages. At such periods, the problem of the effective medicine selection is particularly relevant, so many consumers face the problem, which is better: Erispal or Erispirus?
Brief description of pharmaceuticals
Erispirus and Erispal are medicinal preparations, which are the equal active component of hydrochloride phenspirid. This substance has several essential properties:
Based on information on the components components, it can be argued that Erispirus is an analogue of Erespal.
Erispul, as well as more expensive Erispal, is produced in two forms - syrup and tablets. Tablets are used to treat adult patients and children who have reached fourteen years. Syrup is advisable to use for the treatment of children from two to fourteen years.
In which cases are required
Erispirus and Erispal must be taken at:
- pronounced symptoms of ORZ, Cocal and Corey;
- obstructive pulmonary disease;
- allergic rhinitis;
- chronic bronchitis;
- Asthma seizures;
- Rinofaringitis, otitis and sinusitis.
Erispal and Erispuris: specific use
As the instruction says, these drugs have the same dosage. Tablets are prescribed at once on-time per day (80 mg of active substance). The dosage of the syrup depends on the weight of the child, since it is calculated by the formula: 4 milligrams of the drug for every kilogram of weight.
Erispal and Erispirus: contraindications and side effects
Since Erispal from Erispirus does not differ, both drugs should not be appointed in such cases:
- women during the toasting and breast feeding of the baby;
- the presence of increased sensitivity to components;
- With improper processing of fructose.
If you use Erispal or Erispirus to treat cough, it can cause side effects that manifest themselves:
- insignificant tachycardia;
- allergic reactions;
Erispal and Erispirus: Distinctive features
The main difference between Erispal and Erispirus is in the price ratio . The price of tableted Erispal varies within 375-420 rubles, on syrup - 260-310 rubles. As for Erispirus, he is cheaper. For the tablet form of the drug, you can pay 280-315 rubles, for syrup - 185-220 rubles.
What can replace drugs
If treatment with Erispal and Erispirus for some reason is impossible, many doctors prescribe inspirons patients. This agent is also produced in the form of syrup and tablets. It contains the same substances as in the composition of the erections, therefore it is considered its analogue. According to the reviews of some patients, Inspiron is an even more efficient preparation in the treatment of cough and it is relatively cheap: 195-220 rubles per tablet, 130-155 rubles per syrup.
Indications for the use of inspirone:
- bronchial asthma;
- Overtake of respiratory organs;
- moist cough;
- whooping cough;
Despite the above-described comparison of Ereshpal and Erispirus, the patient must remember that these pharmaceuticals are not suitable for self-treatment and should be taken only to the appointment of a qualified specialist. Otherwise, their reception may cause serious harm to organize.
Vidal : https://www.vidal.ru/drugs/eurespal__24397. GRLS : https://grls.rosminzdrav.ru/Grls_View_v2.aspx?RutingGuid=36B8DC82-C310-40EB-9C56-9E4313F8B10E&t=.
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All people are sick. In the life of each person there are states, during which you have to use drugs so that recovery has come faster. When a person appears a cough, the doctor prescribes drugs for speedy cure. There are many reasons for the appearance of cough: cold, influenza, bronchitis. The preparations of Erispal or its counterparts are very popular in the treatment of drugs, such as Erispirus.
Active substance - Fenspiridum Hydrochloride . This substance has such effects:
- Blocking the breathtaking in bronchi.
- Antispasmodic - removes bronchial spasm.
- Antihistamine (antiallergic).
Erispal acts in such a way that it does not just eliminate cough, but it acts on the cause that caused it. Forms of release - tablets of 80 mg and syrup in dosage 2 mg / ml 150 ml in the vial. You can apply the drug both adults and children. Children are prescribed mainly syrup. Manufacturer of Erespal is the French company "Laboratory of Servier". This is an imported and very high-quality manufacturer, but unfortunately not very cheap.
The drug is quickly absorbed in the body and begins to act after 1.5 - 2 hours, syrup - in an hour. The dosage is calculated on the basis of the age and weight of the patient. Erispal can be taken from 2 years. If the patient has diabetes mellitus, it is impossible to give the medicine syrup, as it contains sucrose.
The medicine has a soothing effect, so it is undesirable to drink jointly with sedative and alcohol, since the soothing effect will be increased. It is necessary to very gently drive vehicles, as drowsiness can occur. During pregnancy and lactation, you need to refrain from the reception.
It is possible to develop individual reactions, such as allergic reactions, various rashes, swelling.
The active ingredient is the same as in Eriespal. Used with the same respiratory diseases. There is a form of tablets of 80 mg and syrup 2 mg / ml (bottle of 150 ml). Children under 18 are recommended to receive in syrup. The manufacturer is the firm "Sandoz". With caution to use with sedatives, during pregnancy, with diabetes, gastrointestinal diseases, sensitivity to fengirid and additional components.
Take inside before meals 1 tablet 2-3 times a day, children - by 4 mg / kg per day . Uses quickly, excreted through the kidneys. The drug is prescribed only by a doctor, no need to engage in self-medication, and does not replace antibacterial therapy, so if necessary, it is accepted in the complex.
- GET: abdominal pain, nausea, vomiting, liquid chair.
- Cardiovascular system: Tachycardia, sharp decrease in pressure (hypotension).
- General condition: strong fatigue, weakness, lethargy.
- Skin: various rashes, erythema.
Erispal and Erispirus are considered counterparts. They have the same active ingredient and mechanism of action. Produced in the same dosage forms and dosages - 80 mg tablets. Syrup 2 mg / ml (bottle of 150 ml).
Used to treat the cause of cough in a complex with antibacterial or anti-inflammatory therapy. Contraindications and side effects are no different from each other. Fenspirid can provoke adverse reactions from the nervous system: fatigue, turbidity of the mind, depression, confusion, panic attacks.
Despite the fact that the medications have the same components, there are several significant differences. The main difference is different manufacturers. "Laboratory of Servier" is a French pharmacological company established in 1954. This is a proven firm that makes quality product. Sandoz is an international company created in the 19th century. This firm produced a variety of diverse drugs.
Due to the fact that various companies are released, they also differ prices. "Servier" is an import company, its drugs are more expensive than their analogues of another manufacturer. Erispal in tablets worth 350-400 rubles , Syrup is worth from 270 to 310 rubles . Erispirus is 2 times cheaper at the price. That is, to undergo a course of treatment with Erispal, you will need to spend approximately 800-1000 rubles The course of Erispirus will be 2 times cheaper.
By efficiency, an imported drug may be better than not imported.
Another difference is in Eriespal, as an auxiliary component, contains Glycyrrhiza Glabra (Lacricians). It is a mucolytic, that is, it makes the sputum not so viscous and it is easier to pump out. Erispirus has no such component.
Fenspirid is a necessary substance in the treatment of cough, if it is caused by the obstruction of the bronchi. The attending physician appoints the medicine that is most suitable for a particular case. But the patient can choose between analogues of this substance.
Erispal is suitable for those who allow the financial opportunity to purchase it. A high-quality manufacturer quickly cures a sick person. For those who have not enough money, you can purchase Erispirus.
Erispal can not be applied to those who have allergic reactions to licorice root, which is present there.
It is worth remembering that before replacing one drug with analogs, You need to consult with your doctor . They have an identical composition, but not always can be replaced.
- Both drugs are similar in composition, but differ in the manufacturer.
- Only the attending physician must determine which one to appoint.
- Fenspirid performs a very important role - relieves inflammation and obstruction of bronchi, which favorably affects the result of treatment.
- Each organism reacts to treatment in different ways. If individual reactions occur, the drug needs to be canceled and inform about this to the doctor.
- But you can buy its full counterparts - other preparations based on Fenspirid